How can you tell the difference between glomerular and non glomerular hematuria?

How can you tell the difference between glomerular and non glomerular hematuria?

According to Fairley et al., 2-5 hematuria is considered “glomerular” when the size and shape of urinary red blood cells vary and the majority have an irregular, distorted outline (Fig. 1). In contrast, hematuria is considered “nonglomerular” when erythrocyte size and shape are uniform (Fig.

What is non glomerular hematuria?

Non-glomerular hematuria A non glomerular etiology is suggested by reddish pink urine, eumorhpic red blood cells, and passage of blood clots. Infections: Pyelonephritis, Cystitis, Prostatitis, Urethritis.

What is transient hematuria?

Transient microscopic hematuria is particularly common in children, present in up to 5% of their urine samples. There are numerous specific causes (see table Some Specific Causes of Hematuria. Urine may be red, bloody, or cola-colored (gross hematuria with oxidation… read more ).

What is painless hematuria?

Painless hematuria (asymptomatic hematuria) Passage of blood or clots in urine in the absence of renal or urinary symptoms.

How can you tell if hematuria is glomerular?

Brown-colored urine, RBC casts, and dysmorphic (small deformed, misshapen, sometimes fragmented) RBCs and proteinuria are suggestive of glomerular hematuria. Reddish or pink urine, passage of blood clots, and eumorphic (normal sized, biconcavely shaped) erythrocytes are suggestive of a nonglomerular bleeding site.

Is hematuria serious?

While in many instances the cause is harmless, blood in urine (hematuria) can indicate a serious disorder. Blood that you can see is called gross hematuria. Urinary blood that’s visible only under a microscope (microscopic hematuria) is found when your doctor tests your urine.

What is the difference between glomerular and nonglomerular bleeding?

Glomerular versus nonglomerular bleeding. . . . . Hematuria is either the microscopic or the macroscopic presence of blood in the urine. Glomerular versus nonglomerular bleeding. The identification of the glomeruli as the source of bleeding is important. Patients with clear evidence of glomerular hematuria do not need to be evaluated

Can a glomerular disease be associated with hematuria?

Although any glomerular disease may be associated with hematuria, most patients also have other signs such as proteinuria, red cell casts, or renal insufficiency. When persistent hematuria is the only manifestation of glomerular disease, one of three disorders is most likely:

What are the signs and symptoms of glomerular disease?

Signs of glomerular bleeding include red cell casts (essentially pathognomonic for glomerular disease), protein excretion exceeding 500 mg/day at a time when there is no gross bleeding, most red cells having a dysmorphic appearance, and brown, coca cola colored urine (table 1).

How to tell if a patient has hematuria?

Hematuria >2-3 RBCs per HPF Microscopic hematuria Yellow urine Concentration Gross hematuria Red/brown urine 1 ml blood Presence of clots = post glomerular disease * Does this patient have hematuria?