What is the PSMC model?

Specifically, the pairwise sequentially Markovian coalescent (PSMC) model uses a hidden Markov framework and identifies historical recombination events across a single diploid genome. The PSMC approach has recently been applied in several genome sequencing projects (e.g. Groenen et al.

How does PSMC work?

PSMC uses the coalescent approach to estimate changes in population size. Estimating TMRCA of the two alleles at each locus is used to create a TMRCA distribution across the genome. And since the rate of coalescent events is inversely proportional to effective population size (Ne), PSMC identifies periods of Ne change.

What does Psmc stand for?


Acronym Definition
PSMC Performance Specified Maintenance Contract (Transit New Zealand)
PSMC Pacific Southwest Mennonite Conference
PSMC Porcine Smooth Muscle Cell (also seen as PVSMC; aka Porcine Vascular Smooth Muscle Cell)
PSMC Past State Master Councilor (Order of DeMolay)

What is pairwise sequentially Markovian coalescent?

The pairwise sequentially Markovian coalescent (PSMC) method uses the genome sequence of a single individual to estimate demographic history covering a time span of thousands of generations. The key factor is the proportion (p) of the genome that the RAD data covers.

What is the full form of PCMC?

Pimpri-Chinchwad Municipal Corporation.

What does LCP mean?


Acronym Definition
LCP Labor Compliance Program (Canada)
LCP Licensed Clinical Psychologist
LCP Large Combustion Plant
LCP Local Community Planning (UK)

What is the full form of PCME in PUC?

PCME – Physics, Chemistry, Mathematics, Electronics.

What does LCP mean on a gun?

Lightweight Compact Pistol
LCP stands for “Lightweight Compact Pistol” and was designed in direct response to customer requests for a compact firearm for use by police as a back-up, and as a defensive handgun for civilian concealed carry needs.

What is the full form of LCP?

LCP Full Form

Full Form Category Term
Link Control Protocol Computer and Networking LCP
Linkage Control Program Networking LCP
Lyris Command Protocol Softwares LCP
Le Chatelier’s Principle Chemistry LCP

Is Pcmb difficult?

At the same time, the difficulty level of a PCMB combination is quite high, since you’ll be managing both Mathematics and Biology, as opposed to a relatively lighter subject (like Computer Science, Physical Education, etc.). Thus, it is important for you to judge if you can manage all of these or not.

Which college is best for PCME?

One of the best PU Colleges in Bangalore for PCME, Surana PU College has highly qualified and excellent faculty who have deep insights in their respective subjects to deliver knowledge to mentor students and prepare them for academic excellence.

What are the results of a PSMC analysis?

The vertical part of these lines points to the time when the two populations split. The red lines are the estimations using PSMC. a-c. Results of simulations with known phase, based on whole genome sequences, RAD with d = 0.001 and RAD with d = 0.0001, respectively. d-f.

Can you use RAD Data for PSMC analysis?

Although originally designed for whole-genome data, we here use simulations to investigate its applicability to reference genome-aligned restriction site associated DNA (RAD) data. We find that RAD data can potentially be used for PSMC analysis, but at present with limitations.

How is PSMC used to estimate population sizes?

However, based on diploid genome sequences of high quality, the recently developed pairwise sequentially Markovian coalescent (PSMC) can estimate trajectories of changes in Ne over considerable time periods.

How can I run PSMC on my own data?

To run PSMC on your own data, you will need to first map your reads to a reference genome before adapting these scripts. Finally, the slides (PDF) from the journal club presentation of this demo are here. Starting from mapped reads, the first step is to produce a consensus sequence in FASTQ format.