What is Hetastarch used for?

What is Hetastarch used for?

Plasma is needed to circulate red blood cells that deliver oxygen throughout the body. Hetastarch is used to treat or prevent hypovolemia (decreased blood plasma volume, also called “shock”) that may occur as a result of serious injury, surgery, severe blood loss, burns, or other trauma.

Is hextend hypertonic?

Hextend and 7.5% hypertonic saline with Dextran are equivalent to Lactated Ringer’s in a swine model of initial resuscitation of uncontrolled hemorrhagic shock. J Trauma.

How do you give hespan?

How is Hespan given? Hespan is injected into a vein through an IV. A healthcare provider will give you this injection.

Is hextend a crystalloid?

Tactical Field Care and TACEVAC Care plasma and RBCs in 1:1 ratio; plasma or RBCs alone; Hextend; and crystalloid (lactated Ringers or Plasma-Lyte A).

What type of fluid is Hetastarch?

Hetastarch is an artificial colloid pharmacologically classified as a plasma volume expander; 0.9% Sodium Chloride Injection is a fluid and electrolyte replenisher.

What are colloids fluids?

Colloids are gelatinous solutions that maintain a high osmotic pressure in the blood. Examples of colloids are albumin, dextran, hydroxyethyl starch (or hetastarch), Haemaccel and Gelofusine.

What is in LR?

Lactated Ringer’s is composed of sodium chloride 6 g/L, sodium lactate 3.1 g/L, potassium chloride 0.3 g/L, and calcium chloride 0.2 g/L. Lactated Ringer’s contains ions of sodium 130 mEq/L, potassium 4 mEq/L, calcium 2.7 mEq/L, chloride 109 mEq/L, and lactate 28 mEq/L.

When do you give hespan?

1. HESPAN® is indicated in the treatment of hypovolemia when plasma volume expansion is desired.
2. The serious adverse events reported in clinical trials are increased mortality and renal replacement therapy renal in critically ill patients.

Why normal saline is not normal?

Saline is not physiological Despite its name, saline is neither “normal” nor “physiological”. Compared to human serum, saline has a nearly 10% higher Na concentration and 50% higher Cl concentration. Table ​1 shows the compositions of human serum, saline, and several commonly used balanced crystalloid fluids.

Is LR more expensive than NS?

The cost difference between a liter of saline and liter of lactated ringers (LR) is about 25 cents. Saline is historically the most widely used fluid, but that doesn’t prove it’s the best.

Is dextran a colloid?

Dextran is a synthetic colloid consisting of mixture of glucose polymers derived from the action of Leuconostoc mesenteroides on sucrose and is currently available in 10% dextran 40 (40 kDa) and 6% dextran 70 (70 kDa). Other side effects of dextrans include allergic reactions and coagulopathy.

Is albumin a colloid?

Albumin, a natural colloid, is synthesized in the liver and is responsible for 80% of the oncotic pressure of the plasma. The molecular weight of albumin is approximately 69 kD. Infusion of the 25% solution expands plasma volume four to five times the volume infused5 (see Table 2).

How is hextend injected into the blood stream?

Hextend is injected into a vein through an IV. A healthcare provider will give you this injection. Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely while you are receiving Hextend.

What do you need to know about hextend treatment?

Hextend is injected into a vein through an IV. A healthcare provider will give you this injection. Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely while you are receiving Hextend. Your blood will also need to be tested daily during treatment.

Is it safe to use Hess fluid resuscitation?

However, the FDA issued a safety communication on HESs (Hespan, Hextend, and Voluven) in November 2013. The warning noted an increased risk in mortality and renal replacement therapy associated with the use of these products as used to treat critically ill patients [ 14 ].

How many milligrams of hextend should I take?

Total dosage and rate of infusion depend upon the amount of blood or plasma lost and the resultant hemoconcentration as well as age, weight, and clinical condition of the patient. The amount usually administered is 500 to 1000 mL.