What does CMV IgG positive mean?

What does CMV IgG positive mean?

A positive test for CMV IgG indicates that a person was infected with CMV at some time during their life but does not indicate when a person was infected. This applies for persons ≥12 months of age when maternal antibodies are no longer present.

What happens if you test positive for CMV?

Although this person will test positive for CMV antibodies, he or she is healthy, has no evidence of disease and will not ordinarily transmit the virus to another person. However, if there is a suppression of the immune system, the virus may reactivate, shed viral particles and cause disease.

How do they test for CMV in adults?

Your healthcare provider may also order a test called polymerase chain reaction (PCR) to hunt for the DNA of CMV in your urine, saliva, blood, CSF, or biopsy tissue. He or she may also order a viral culture test from any of these sample types.

What is a normal CMV IgG level?

0.8 AI or less: Negative – No significant level of detectable CMV IgG antibody. 0.9-1.0 AI: Equivocal – Repeat testing in 10-14 days may be helpful. 1.1 AI or greater: Positive – IgG antibody to CMV detected, which may indicate a current or past CMV infection.

Does CMV go away?

There’s no cure for CMV. The virus stays inactive in your body and can cause more problems later. This reactivation is most common in people who’ve had stem cell and organ transplants.

Does CMV shorten your life?

CMV has been associated with impaired immunity, increased morbidity due to cardiovascular diseases, and reduced lifespan and health span – the length of life spent in good health.

How is the Zeus Elisa IgG test used?

The ZEUS ELISA Cytomegalovirus (CMV) IgG Test System is an enzyme-linked immunosorbent assay intended for the qualitative detection of IgG class antibodies to cytomegalovirus in human serum. This test system is intended to be used to evaluate serologic evidence of previous or primary infection with CMV, and is for in vitro diagnostic use.

Can a IgM test be used to diagnose CMV?

The presence of CMV IgM cannot be used by itself to diagnose primary CMV infection because IgM can also be present during secondary CMV infection. IgM positive results in combination with low IgG avidity results are considered reliable evidence for primary infection, with limitations of avidity testing described below.

When do IgG antibodies mature after CMV infection?

IgG avidity assays measure the binding strength between IgG antibodies and virus that can help distinguish a primary CMV infection from a past infection. Following primary CMV infection, IgG antibodies have low binding strength (low avidity) then over 2-4 months mature to high binding strength (high avidity).

How are newborns tested for congenital CMV infection?

Laboratory Diagnosis of Congenital CMV Infection in Newborns The standard laboratory test for diagnosing congenital CMV infection is polymerase chain reaction (PCR) on saliva, with urine usually collected and tested for confirmation. The reason for the confirmatory test on urine is that most CMV seropositive mothers shed CMV in their breast milk.