Is the movie Extraordinary Measures a true story?

Published on by Paul Reynolds

Is the movie Extraordinary Measures a true story?

Extraordinary Measures is a 2010 American medical drama film starring Brendan Fraser, Harrison Ford, and Keri Russell. The film is based on the true story of John and Aileen Crowley, whose children have Pompe’s disease.

Is Extraordinary Measures on Netflix?

Sorry, Extraordinary Measures is not available on American Netflix.

What was the disease in extraordinary measures?

During the weekend, a film called Extraordinary Measures , starring Harrison Ford and Brendan Fraser, debuted in theatres. Based on a true story, the film highlights a condition called Pompe disease.

How are they trying to help cure Pompe disease in the movie Extraordinary Measures?

In 2006, the FDA approved the use of Myozyme, which is manufactured and marketed by Genzyme Corporation, based on Duke’s research. As a result, the children portrayed in the movie, and those who are living with Pompe worldwide, were treated with Myozyme and given their first fighting chance at life.

What happened Brendan Fraser?

During a hiatus from film acting, Fraser found success in television, with supporting roles in the History miniseries Texas Rising (2015), the Showtime drama series The Affair (2016–2017), the FX anthology series Trust (2018) and the DC Universe / HBO Max action series Doom Patrol (2019–present).

Is Extraordinary Measures on Amazon Prime?

Watch Extraordinary Measures | Prime Video.

What disease do Megan and Patrick Crowley suffer from?

On a Friday the 13th some 20 years ago, 15-month-old Megan Crowley was diagnosed with Pompe disease. A few weeks later, so was her newborn brother, Patrick. Even the doctor who diagnosed the two children didn’t know much about the disease.

What is Pompe’s disease?

Description. Collapse Section. Pompe disease is an inherited disorder caused by the buildup of a complex sugar called glycogen in the body’s cells. The accumulation of glycogen in certain organs and tissues, especially muscles, impairs their ability to function normally.

Is the movie Extraordinary measures about Pompe disease?

When the film Extraordinary Measures debuts on January 22, it will tell the story of one man’s quest to obtain treatment for his children who suffer from a rare metabolic disorder called Pompe disease.

What was the first treatment for Pompe disease?

The real story began 20 years ago at Duke University Medical Center when pediatric geneticist Y.T. Chen, MD, PhD, began work on the first and only life-saving treatment for Pompe. In 2006, the FDA approved the use of Myozyme, which is manufactured and marketed by Genzyme Corporation, based on Duke’s research.

What happens to the enzyme in Pompe disease?

Pompe disease results when mutations occur in the gene that triggers the production of an enzyme called acid alpha-glucosidase (GAA). That enzyme is responsible for helping the body break down glycogen (sugar).

Who is the mom in extraordinary measures Harrison Ford?

Awesome, realistic, portrayals by both men. Not to be upstaged, the mom, Aileen (Keri Russell) has her own moments and makes this EXTRAORDINARY scenario very believable. John mixes his emotional experience as a parent with the profit motivated Zymagen drug firm. Aileen is at his side-most of the time.

https://www.youtube.com/watch?v=VjCDUw7_Gfg

Is the movie Extraordinary Measures a true story?

Venture capitalist John Crowley (played by Brendan Fraser) has two children with the neuromuscular disorder Pompe disease. Searching for a way to help his children, John finds a scientist, Dr. Robert Stonehill ( Harrison Ford), who is developing a treatment.

What happens in Extraordinary Measures?

A drama centered on the efforts of John and Aileen Crowley to find a researcher who might have a cure for their two children’s rare genetic disorder. A drama centered on the efforts of John and Aileen Crowley to find a researcher who might have a cure for their two children’s rare genetic disorder.

Who is the real Robert Stonehill?

In reality, John Crowley is the name of the person who started the biomedical company, but the real Dr Stonehill who developed the cure is in fact Chen Yuan-tsong (陳垣崇), director of Academia Sinica’s Institute of Biomedical Sciences.

Where can I find the movie Extraordinary Measures?

Watch Extraordinary Measures | Prime Video.

What is the cause of the disease that the children have in extraordinary measures?

It is an autosomal recessive genetic disorder caused by a deficiency of the lysosomal hydrolase acid alpha-glucosidase, which breaks down glycogen. Without enough of this enzyme, patients experience an accumulation of glycogen in the body’s tissues. Cardiac and skeletal muscle tissues are affected primarily.

What is the average life expectancy for a child with this disorder according to the beginning of the movie Extraordinary Measures?

John Crowley’s (Brendan Fraser) youngest children were diagnosed with the very rare Pompe Disease, and are confined to wheelchairs for their lives. The average life span for children suffering from the disease rarely goes past nine, and his daughter Megan (Meredith Droeger) has just turned eight.

What disease is the father reading about Extraordinary Measures?

When the film Extraordinary Measures debuts on January 22, it will tell the story of one man’s quest to obtain treatment for his children who suffer from a rare metabolic disorder called Pompe disease. The real story began 20 years ago at Duke University Medical Center when pediatric geneticist Y.T.

How do people get Pompe?

Pompe disease is a rare (estimated at 1 in every 40,000 births), inherited and often fatal disorder that disables the heart and skeletal muscles. It is caused by mutations in a gene that makes an enzyme called acid alpha-glucosidase (GAA).

Was Dr Stonehill’s theory correct?

Dr. Stonehill, while brilliant and confident in his scientific research and theories, admits that ultimately his work is only theoretical, and not yet empirically proven.

What is Extraordinary Measures?

Extraordinary measures are those that are based on medication or treatment which cannot be applied without incurring severe pain, costs or other inconveniences. Their application, however, would not give the patient any justified hope for a commensurate improvement in his health.

What is Pompe’s disease?

Definition. Pompe disease is a rare (estimated at 1 in every 40,000 births), inherited and often fatal disorder that disables the heart and skeletal muscles. It is caused by mutations in a gene that makes an enzyme called acid alpha-glucosidase (GAA).

What does extraordinary measures mean?

Who are the actors in the movie Extraordinary Measures?

Extraordinary Measures. Extraordinary Measures is a 2010 American medical drama film starring Brendan Fraser, Harrison Ford, and Keri Russell. It was the first film produced by CBS Films, the film division of CBS Corporation, who released the film on January 22, 2010.

What was the plot of the book Extraordinary Measures?

John takes on the task full time, working with venture capitalists and then rival teams of researchers. Time is running short, Stonehill’s angry outburst hinder the company’s faith in him, and the profit motive may upend John’s hopes. The researchers race against time for the children who have the disease.

Who are the companies in extraordinary measures based on?

The small start-up company Priozyme was based on Oklahoma City-based Novazyme. The larger company, called Zymagen in the film, was based on Genzyme in Cambridge, Massachusetts. Novazyme was developing a protein therapeutic, with several biological patents pending, to treat Pompe Disease, when it was bought by Genzyme.

Who are John and Aileen in extraordinary measures?

John, an advertising executive, contacts Robert Stonehill ( Harrison Ford ), a researcher in Nebraska who has done innovative research for an enzyme treatment for the rare disease. John and Aileen raise money to help Stonehill’s research and the required clinical trials.