Does Reclast have a generic?
Reclast is a brand name for the generic drug zoledronic acid. It belongs to a class of osteoporosis treatments known as bisphosphonates, which help decrease bone turnover.
Is Reclast the same as Zometa?
Although the “same” drug, Zometa® and Reclast® are actually very different. Clinicians should refer to product information and clinical research on dosing, adverse effects, and treatment guidelines for each product.
Is Reclast the same as alendronate?
Fosamax (alendronate sodium) and Reclast (zoledronic acid) are bisphosphonates used to treat and prevent osteoporosis, and to treat Paget’s disease.
Is aclasta the same as Reclast?
Zoledronic acid (Reclast®, Aclasta®) is an intravenous, highly potent aminobisphosphonate approved worldwide, including in the USA, EU and Japan for use in patients with primary or secondary osteoporosis or low bone mass (approved indications vary between countries).
Who should not take Reclast?
You should not take Zolendronic acid if you are pregnant, breast feeding, have kidney problems, or have low blood calcium.
Who should not have Reclast infusion?
Reclast is contraindicated in patients with creatinine clearance less than 35 mL/min and in those with evidence of acute renal impairment. A 5 mg dose of Reclast administered intravenously is recommended for patients with creatinine clearance greater than or equal to 35 mL/min.
How many doses of Reclast can you have?
A 5 mg dose of Reclast administered intravenously is recommended for patients with creatinine clearance >35 mL/min [see Warnings and Precautions (5.3)]. The recommended regimen is a 5 mg infusion once a year given intravenously over no less than 15 minutes.
Does Reclast cause hair loss?
Like other bisphosphonate medications, Reclast has been linked to hair loss and/or thinning of hair in some patients.
Does Reclast really work?
Millions of Americans take bisphosphonates by mouth to prevent bone loss from osteoporosis or steroid medications, most often once a week or once a month. One study found that Reclast, or zoledronic acid, given through injection once a year, may actually work even better.
How safe is Reclast?
There are concerns about the long-term safety of bisphosphonates (such as Reclast) as long-term use has been associated with atypical femur fractures, osteonecrosis of the jaw, and esophageal cancer. The risk of osteonecrosis of the jaw is greater in those who have received chemotherapy, radiation, or steroids.
Has anyone died from Reclast?
The FDA warning says that kidney failure is a rare but serious complication for at-risk patients taking Reclast. The drug was approved in April 2007. Two dozen cases of kidney impairment or failure, including five deaths, were reported in a safety review published in January 2009.
Are there any side effects from Novartis Reclast?
It sometimes looks that way. The consumer group Public Citizen wants the U.S. Food and Drug Administration to do what Canada apparently did five months ago – tell Novartis to warn physicians and consumers about a dangerous link between a widely-used osteoporosis drug and serious renal toxicity, which can result in death.
Is the drug Reclast identical to the Canadian drug?
The drug is called Reclast in the U.S. and is identical to the Canadian version. Five months later, the FDA has done nothing, said Public Citizen’s Sidney Wolfe, M.D., in a letter to FDA Commissioner Margaret Hamburg, M.D.
How often should you take Reclast for osteoporosis?
“We therefore urge the FDA to immediately require that Novartis issue a similar “Dear Doctor Letter” to all physicians in the U.S.” Reclast is given once a year for treatment of osteoporosis in men and postmeopausal women and once every two years for prevention of osteoporosis in postmenopausal women.